Detalles de la búsqueda
1.
Comprehensive Impurity Profiling of mRNA: Evaluating Current Technologies and Advanced Analytical Techniques.
Anal Chem;
96(9): 3886-3897, 2024 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38377434
2.
Multi-dimensional technology - Recent advances and applications for biotherapeutic characterization.
J Sep Sci;
47(5): e2300928, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38471977
3.
Novel Multidimensional Liquid Chromatography Workflow with In-Loop Enzymatic Digests of Multiple Heart-Cuts for Fast and Flexible Characterization of Biotherapeutic Protein Variants.
Anal Chem;
95(7): 3629-3637, 2023 02 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36745752
4.
Comprehensive Analysis of Photoreceptor Outer Segments: Flow Cytometry Characterization and Stress-Driven Impact on Retinal Pigment Epithelium Phagocytosis.
Int J Mol Sci;
24(16)2023 Aug 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37629070
5.
Physicochemical and Functional Characterization of Differential CRISPR-Cas9 Ribonucleoprotein Complexes.
Anal Chem;
94(2): 1432-1440, 2022 01 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34958212
6.
Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches.
Analyst;
146(3): 747-769, 2021 Feb 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33410843
7.
Therapeutic Fc-fusion proteins: Current analytical strategies.
J Sep Sci;
44(1): 35-62, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-32914936
8.
Targeted Bottom-up Characterization of Recombinant Monoclonal Antibodies by Multidimensional LC/MS.
Anal Chem;
92(19): 13420-13426, 2020 10 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32901474
9.
Fast and Automated Characterization of Monoclonal Antibody Minor Variants from Cell Cultures by Combined Protein-A and Multidimensional LC/MS Methodologies.
Anal Chem;
92(12): 8506-8513, 2020 06 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-32441930
10.
Development of a 3D-LC/MS Workflow for Fast, Automated, and Effective Characterization of Glycosylation Patterns of Biotherapeutic Products.
Anal Chem;
92(6): 4357-4363, 2020 03 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32079391
11.
Analysis of the human chorionic gonadotropin protein at the intact level by HILIC-MS and comparison with RPLC-MS.
Anal Bioanal Chem;
412(18): 4423-4432, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32377867
12.
Identification and semi-relative quantification of intact glycoforms by nano-LC-(Orbitrap)MS: application to the α-subunit of human chorionic gonadotropin and follicle-stimulating hormone.
Anal Bioanal Chem;
412(23): 5729-5741, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32642835
13.
Assessing TCR identity, knock-in efficiency, and potency for individualized TCR-T cell therapy.
J Immunol Methods;
517: 113491, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37187316
14.
Comprehensive UHPLC- and CE-based methods for engineered Cas9 characterization.
Talanta;
252: 123780, 2023 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35988299
15.
Monitoring multiple quality attributes of a complex Fc-fusion protein during cell culture production processes by mD-LC-MS peptide mapping.
Talanta;
246: 123519, 2022 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35525056
16.
Real-time monitoring of antibody quality attributes for cell culture production processes in bioreactors via integration of an automated sampling technology with multi-dimensional liquid chromatography mass spectrometry.
J Chromatogr A;
1672: 463067, 2022 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35462311
17.
Extending the performance of FcRn and FcγRIIIa affinity liquid chromatography for protein biopharmaceuticals.
J Chromatogr A;
1682: 463518, 2022 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36155073
18.
Challenges and Strategies for a Thorough Characterization of Antibody Acidic Charge Variants.
Bioengineering (Basel);
9(11)2022 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36354552
19.
Inter-laboratory study to evaluate the performance of automated online characterization of antibody charge variants by multi-dimensional LC-MS/MS.
Talanta;
234: 122628, 2021 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34364437
20.
Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation.
MAbs;
13(1): 1893427, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33682619